Feel like your skin’s lost its glow? Unlike traditional injectables, Polynucleotides don’t add volume, instead, they boost your skin’s natural ability to regenerate, repair and glow.

ADVANCED SKIN REJUVENATION | CLINICS ACROSS THE UK
Choose your nearest Kiss clinic when booking to view practitioner availability and consultation options.

ADVANCED SKIN REJUVENATION | CLINICS ACROSS THE UK
Choose your nearest Kiss clinic when booking to view practitioner availability and consultation options.
REAL KISS PATIENTS
Here are some polynucleotides before and after results from Kiss Aesthetics clients. Polynucleotide treatments are designed to support skin repair, improve skin quality and encourage regeneration from within, rather than adding volume or changing your facial features.
Polynucleotides are an advanced regenerative skin treatment designed to improve skin quality, support tissue repair and encourage healthier, stronger skin from within.
Derived from highly purified DNA fragments, polynucleotides work by creating an environment that supports your skin's natural healing and renewal processes. Rather than adding volume or changing facial contours, they help improve hydration, elasticity, skin texture and overall skin health.
One of the reasons polynucleotides have become so popular is their versatility. They can be used on delicate areas such as the under-eyes, as well as the face, neck and other areas, including the hands and body, that are showing signs of ageing, skin damage or reduced skin quality.
They are designed to improve the quality of the skin itself.
Results develop gradually as your skin becomes healthier, stronger and more resilient over the weeks following treatment. Many clients notice improvements in hydration, texture, firmness and radiance, with the skin appearing fresher and more rejuvenated without looking treated.
At Kiss Aesthetics, we often recommend polynucleotides as part of a personalised skin rejuvenation plan for clients who want natural-looking results and healthier skin over the long term. Your practitioner will assess your skin concerns, treatment goals and suitability before recommending whether polynucleotides are right for you.
What Can Polynucleotides Help With?
Polynucleotides are designed to support the skin's natural repair processes, helping to improve overall skin quality, resilience and appearance over time.
Rather than adding volume or changing facial contours, polynucleotides work within the skin to encourage regeneration, improve hydration and support healthier skin function.
Many clients choose polynucleotides because they want natural-looking skin rejuvenation that focuses on improving the condition of their skin rather than masking concerns.
Polynucleotides can help with:
WHO ARE POLYNUCLEOTIDES FOR?
Are Polynucleotides Right For Me?
Polynucleotides may be suitable if your skin feels thinner, duller, weaker or less resilient than it used to. They are often chosen by clients who want to improve skin quality, support repair and achieve fresher-looking skin without adding volume or changing their facial features.
This treatment can be particularly helpful if you are concerned about fine lines, crepey skin, under-eye ageing, poor elasticity, dehydration, skin laxity or a tired-looking complexion.
Polynucleotides are also a good option for clients who want a regenerative approach to skin rejuvenation. Rather than simply masking concerns, they support the skin’s natural repair processes over time.
Your practitioner will assess your skin, medical history and treatment goals before confirming whether polynucleotide treatment is right for you.
Polynucleotides can be used on several areas where the skin is delicate, ageing, damaged or showing signs of reduced quality.
Polynucleotides may be used on:
• Under-eyes (very popular)
• Face
• Neck
• Décolletage
• Around the mouth
• Jawline area
• Body areas with fine lines or crepey texture






Why Choose Kiss Aesthetics for Your Regenerative Skin Treatments Like Polynucleotides
At Kiss Aesthetics, we use polynucleotides for clients who want to improve skin quality, support repair and achieve fresher-looking skin without adding volume or changing their natural features.
Our approach is always personalised. Some clients come to us for under-eye rejuvenation, while others want to improve fine lines, skin texture, elasticity or overall skin quality across the face and neck.
Your practitioner will assess your skin, medical history and goals before recommending whether polynucleotides are right for you. In some cases, they may be used on their own. In others, they may work best as part of a wider skin rejuvenation plan.
KISS AESTHETICS SKIN REJUVENATION
Every polynucleotide appointment begins with a detailed consultation. Your practitioner will assess your skin concerns, skin quality, medical history and treatment goals before discussing whether polynucleotides are the most suitable option for you.
During your consultation, we'll explain how polynucleotides work, the number of sessions that may be recommended and what kind of improvements you can realistically expect over time.
Once your treatment plan has been agreed, the treatment area will be prepared and polynucleotides will be carefully injected into the selected area using advanced techniques designed to support skin regeneration, tissue repair and overall skin health.
It is important to remember that polynucleotide results develop gradually. As your skin undergoes its natural repair processes, improvements become visible over the following weeks, helping the skin appear healthier, stronger and more refreshed.
RESULTS SEEN
Typically within 4–8 weeks, with continued improvement as the skin regenerates.
RESULTS LAST
Results can last several months, with maintenance helping to support long-term skin quality.
NO. OF SESSIONS
Most clients benefit from a course of 2–3 treatments spaced several weeks apart.
APPOINTMENT DURATION
Approximately 30–45 minutes, including consultation and treatment planning.
PAIN
Most clients find Polynucleotide injections comfortable. Some report a mild stinging sensation.
DOWNTIME
Minimal. Mild redness, swelling or tenderness may occur and usually settles within a few days.
SIDE EFFECTS
Temporary redness, swelling, bruising or tenderness at the treatment sites may occur.
TIME BETWEEN SESSIONS
Typically 2–4 weeks between the initial 2-3, with maintenance sessions recommended.
You may also be interested in:
Improve skin hydration, texture and glow with Profhilo. It's designed to boost skin quality and radiance from within. Commonly booked with Polynucleotides.
Restore deeper facial support and improve skin firmness with Profhilo Structura, a regenerative treatment designed to target age-related fat pad changes and facial laxity.
Improve skin texture, reduce signs of ageing and support faster skin repair for a brighter, more youthful complexion.
Not sure whether Polynucleotides are right for you? Book a consultation and we’ll guide you through the best treatment options for you.
Polynucleotide treatments are available at selected Kiss Aesthetics clinics across the UK. Availability may vary between locations depending on practitioner schedules, consultation availability and treatment demand.
Whether you are searching for polynucleotides in London, polynucleotides in Manchester, polynucleotides in Birmingham, polynucleotides in Cardiff or polynucleotide treatment near me, our team can help you explore the most suitable treatment options and arrange a consultation at your preferred clinic.
Simply book your consultation below and select your preferred clinic during the booking process.
SKIN REPAIR WITH POLYNUCLEOTIDES
Polynucleotides are regenerative injectable treatments designed to improve skin quality by supporting the skin's natural repair processes. Rather than adding volume like dermal fillers, polynucleotides help stimulate tissue repair, improve hydration, support collagen production and enhance overall skin health.
Polynucleotides work by encouraging the skin to repair and regenerate itself. Once injected, they help improve cellular function, support collagen and elastin production, enhance hydration and improve skin quality over time. Results develop gradually as the skin becomes healthier, stronger and more resilient.
Polynucleotides can be used on several areas of the face and body, including:
They are particularly popular for treating delicate areas where skin quality, hydration and texture are the main concerns.
Polynucleotides and skin boosters work differently and are often used for different goals. Skin boosters focus primarily on improving hydration and radiance, while polynucleotides are designed to support tissue repair, collagen production and skin regeneration. During your consultation, your practitioner will recommend the most suitable treatment based on your skin concerns.
Yes. Polynucleotides are one of the most popular treatments for the under-eye area. They can help improve crepey skin, fine lines, skin quality and overall appearance while supporting healthier-looking skin around the eyes.
Most clients benefit from a course of 2-3 treatments spaced several weeks apart. The exact number will depend on your skin quality, age, treatment area and desired outcome. Your practitioner will create a personalised treatment plan during your consultation.
Polynucleotide results develop gradually. Some improvements in skin hydration and texture may be noticed within a few weeks, while collagen stimulation and regenerative benefits continue to develop over the following months.
Results vary between individuals, but many clients enjoy improvements for several months following a treatment course. Maintenance treatments may be recommended to help maintain optimal skin quality and long-term results.
Yes. Polynucleotides are commonly chosen by clients concerned about ageing skin, reduced elasticity, fine lines, crepey texture and loss of skin quality. They are designed to support healthier, stronger skin rather than simply masking signs of ageing.
Polynucleotide treatments are available at selected Kiss Aesthetics clinics across the UK. Simply choose your preferred location when booking and our team will guide you through consultation availability and treatment options.
Ready to Book Polynucleotides?
Book a consultation at your nearest Kiss clinic and together we'll create a personalised treatment plan for skin repair and rejuvenation.